What is Polycystic Ovarian Syndrome?

I'm sure you are not familiar with polycystic ovary syndrome, and even many friends have never heard of this name. Yes, it has nothing to do with men, but it is closely related to their mothers and wives. But what exactly is polycystic ovary syndrome? Will it cause serious harm to the body? Let's take a look at it together.

The etiology of pCOS is still unclear, and the pathological mechanisms involved are very complex. It is generally believed to be related to hypothalamic-pituitary-ovarian axis dysfunction, adrenal dysfunction, genetics, metabolism and other factors.

1. Genetics

pCOS is an autosomal dominant inheritance, or X-linked (sex-linked) inheritance, or a disease caused by gene mutation. Most patients have a 46,XX karyotype, and some patients have chromosomal aberrations or mosaicism such as 46,XX/45,XO/46,XX/46,XXq and 46,XXq.

2. Adrenarche hypothesis

pCOS originates from prepubertal adrenal disease, that is, when subjected to strong stress stimulation, the reticular zone secretes too much androgen, which is converted into estrogen outside the gonads, causing feedback disturbances in the GnRH-GnH release rhythm of the Hp axis, an increase in the LH/FSH ratio, and a subsequent increase in ovarian androgen production, that is, the adrenal glands and ovaries jointly secrete more androgen, leading to hyperandrogenemia. Hyperandrogenemia causes thickening of the ovarian capsule fibrosis, inhibits follicular development, and causes ovarian cystic enlargement and chronic anovulation.

Traditional Chinese medicine believes that this disease is mainly caused by kidney deficiency, phlegm and dampness, qi stagnation and blood stasis, damp heat in the liver meridians, etc., which lead to dysfunction of the kidney-tiangui-chongren-uterus axis, resulting in amenorrhea and infertility.

After reading what we have carefully prepared for you, I wonder if it is helpful to you. At the same time, the ovary is one of the important organs of female friends. In addition to bilateral polycystic ovary syndrome, there are many other diseases. Therefore, in daily life, you should pay attention to keeping warm, eat regularly, exercise more, and go to the hospital for regular check-ups.