What are the causes of uterine fibroids? Can uterine fibroids be inherited?

Uterine fibroids are a common benign tumor. Many patients do not detect the disease in the early stages. With age, the disease will gradually worsen and the tumor will grow larger. Women of childbearing age have a high incidence of the disease. Patients should detect the disease immediately because it is an important factor in female infertility. Let us understand its causes.

1. Risk factors: Estrogen, young menarche, nulliparity, late childbearing, obesity and other factors can increase the risk of uterine fibroids.

2. Sex hormones and their receptors: Modern medicine believes that uterine fibroids are a type of hormone-dependent tumor. Estrogen and progesterone synergistically promote the growth of fibroids. The main mechanism may be that estrogen in the follicular phase increases the estrogen receptors on the uterine smooth muscle, and then progesterone in the luteal phase promotes the mitosis of fibroids, thereby stimulating the growth of fibroids.

3. Genetic factors: 25-50% of uterine fibroids have cytogenetic abnormalities, including exchange of chromosome 12 and chromosome 17 fragments, rearrangement of chromosome 12, and deletion of chromosome 7.

4. Cytokines and extracellular mediators: The expression levels of various growth factors and their receptors in uterine fibroids are increased. They are considered to be mediators or effectors of increased ovarian hormones during the formation of uterine fibroids, but the possibility of abnormal primary regulation of one or more growth factors cannot be ruled out.

5. Environmental and lifestyle factors: Bad work and rest schedules and lifestyle habits such as smoking, drinking, unhygienic sex, and environmental pollution can lead to menstrual disorders and increase the possibility of uterine fibroids.

From the above introduction, it can be seen that although uterine fibroids are benign tumors, they have a certain hereditary nature, so patients must actively and thoroughly cure the disease. In addition, patients should eat more light food and take more care of the disease after treatment.