What are the common vulvar leukoplakia diseases? Vulvar leukoplakia can be said to be a relatively common gynecological disease, which has caused harm to too many female friends. Understanding the symptoms of vulvar leukoplakia can help us detect the disease in time and is also very helpful for treatment. 1. Mixed vulvar dystrophy It is manifested as local epithelial hyperplasia and hypertrophy on the basis of atrophic type. Microscopically, hyperplastic islands can be seen in the atrophic lesion area. 2. Leukoplakia vulvae with atypical hyperplasia On the basis of the above-mentioned various types of vulvar leukoplakia, atypical hyperplasia can be accompanied, but hyperplastic vulvar leukoplakia is more common. Under the microscope, it can be seen that the prickle cell layer is arranged without layers, the cells are of different sizes, and some have increased divisions. It can be divided into three levels: mild, moderate, and severe according to the degree. Atypical hyperplasia is mild when it is limited to the deep epidermis, moderate when it involves the middle part of the epidermis, and severe when it involves the entire layer. 3. Proliferative malnutrition The vulvar skin is thickened and dark red, with many raised white spots and dark red areas, showing a mottled lichenification. Microscopic epithelial hyperplasia, irregular thickening of the prickle cell layer, elongated epithelial legs, obvious dermal papillae, hyperkeratosis of the epithelial surface, and chronic inflammatory cell infiltration in the dermis are common symptoms of vulvar leukoplakia. Lichen sclerosus dystrophy At first, it is a small white papule with irregular edges and a flat surface, which gradually merges into white spots, so it is called moss, and further merges into large white spots. After the lesion is fully developed, the skin becomes wrinkled, like brown paper, thin, hard, and brittle, and the elasticity disappears, gradually forming atrophy of the entire vulva. Under the microscope, the epithelium atrophies, the epithelium hyperkeratosis, the collagen fibers of the dermis become hyaline, and the middle area of the dermis is infiltrated with chronic inflammatory cells. |
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