How to detect cervical warts in time

Cervical warts are a very difficult disease to treat. Its arrival makes many patients suffer. If cervical warts can be discovered early during treatment, timely response can be made, which is very important for the patient's treatment. Therefore, for patients, diagnosis is the key. So, how to quickly diagnose cervical warts? I believe this is a topic that many people are concerned about. Let us now take a closer look at it. Only after truly understanding this disease will it be helpful for its treatment.

1. Acetic acid whitening test. Apply 3-5% acetic acid to the wart for 2-5 minutes. The lesion will turn white and slightly raised. Anal lesions may take 15 minutes. The principle of this test is the result of protein coagulation and whitening with acid. The keratin produced by HPV-infected cells is different from that produced by normal uninfected epithelial cells. Only the former can be decolorized by acetic acid. The acetic acid whitening test has a high sensitivity for detecting HPV, and it is better than conventional tests for observing histological changes. However, false positives occasionally occur in cases of epithelial thickening or traumatic abrasions, and the false positive whitening signs appear unclear and irregular. The US CDC reminds that the acetic acid whitening test is not a specific test and false positives are common.

2. Immunohistological examination. The peroxidase antiperoxidase method (PAP) is commonly used to show the viral protein in the warts to prove the presence of viral antigens in the wart lesions. When HPV protein is positive, a weak red positive reaction may appear in the superficial epithelial cells of cervical warts.

3. Histochemical examination. Take a small amount of lesion tissue to make a smear and stain it with specific anti-human papillomavirus antibodies. If there is a viral antigen in the lesion, the antigen and antibody will bind. In the peroxidase antiperoxidase (PAP) method, the nucleus can be stained red. This method is highly specific and rapid, which is helpful for diagnosis.