Why is menopause difficult to cure?

Why is menopause difficult to cure? Every woman will experience menopause, a physiological phenomenon, so you should know about it in advance. Menopause refers to the decline of ovarian function and the cessation of menstruation. The treatment of menopause is also a concern for many women. There are four treatment methods for menopause. In principle, the goal should be to maintain the health of the body. For example, long-term medication is required to prevent postmenopausal degenerative diseases.

1. Etiological treatment

During the reproductive period, women participate in the coordination of physiological activities due to the cyclical changes in the blood of estrogen and progesterone, which becomes an important factor in stabilizing the internal environment of women and maintaining health. After menopause, due to the continuous low estrogen and progesterone levels, women's physical and mental functions are disordered, and the body produces a series of degenerative lesions, resulting in poor physical health for some women. Etiological treatment is given to these health problems caused by estrogen deficiency.

2. Physiological supplementation

The purpose is to make the organs of postmenopausal women function physiologically as much as possible to maintain their health, not to restore their endocrine status to the level of the ovarian cycle during the reproductive period, which is physiological supplementation. Physiological supplementation mostly advocates the use of natural estrogen, that is, the chemical structure of estrone, estradiol and estriol.

3. During the menopausal transition period, hormone replacement therapy (HRT) should focus on progesterone supplementation

During the menopausal transition period, the growth and development disorders of follicles gradually increase, and finally the functional follicles disappear from the ovaries. The corresponding changes in estrogen and progesterone during this period are: first, there is a relative lack of progesterone, then lack; estrogen deficiency changes periodically, although there may be a transient relative excess, the total amount gradually decreases, and finally to lack, forming a relatively excessive or single unopposed estrogen stimulation for a long time. Some women may have different degrees of proliferative changes in the endometrium, and even malignant changes. Therefore, this period should be based on periodic supplementation of progesterone to adjust the menstrual cycle and prevent endometrial proliferative lesions. As estrogen gradually becomes deficient, estrogen can be supplemented at the same time.

4. HRT in postmenopause should focus on estrogen supplementation

The activity of ovarian follicles basically stops in the early postmenopause period. The blood estradiol concentration drops from about 150-1500pmol/L in the reproductive period to below 80pmol/L within 1-2 years, which is lower than the basic level for maintaining the physiological functions of the body's organs. Endometrial atrophy is completed within 2-3 years after menopause, and the rate of bone loss is fastest within 1-3 years after menopause. Corresponding degenerative changes occur in various organs throughout the body. Therefore, to prevent postmenopausal degenerative lesions, timely and long-term estrogen supplementation should be used. To counteract the side effects of estrogen on endometrial hyperplasia, those with a uterus need to add progesterone.

The four treatment methods for menopause are etiological treatment, physiological supplementation, hormone replacement therapy (HRT) during the menopausal transition period should focus on hormone supplementation, and HRT in the late menopause period should focus on hormone supplementation. I hope this article can be useful to female friends, so that they can find the right treatment method for themselves and have a healthy life.