What are the laboratory auxiliary examination items for diagnosing ectopic pregnancy?

Before miscarriage or rupture and bleeding occurs, the symptoms of ectopic pregnancy are generally not obvious, and the diagnosis requires the following laboratory auxiliary tests.

1. Urine pregnancy test

Urine pregnancy test is a relatively simple and quick method to diagnose ectopic pregnancy. If the urine pregnancy test result is positive, ectopic pregnancy can be preliminarily diagnosed. If the result is negative, the next step of β-human chorionic gonadotropin test is required.

2. Quantitative detection of blood β-human chorionic gonadotropin

Quantitative detection of blood β-human chorionic gonadotropin is an important method for early diagnosis of ectopic pregnancy and can assist in determining the activity of the embryo. The blood β-human chorionic gonadotropin value of patients with ectopic pregnancy is generally lower than that of normal intrauterine pregnancy. In addition, after conservative drug treatment or surgical treatment of ectopic pregnancy, β-human chorionic gonadotropin levels should also be monitored to ensure early detection of the presence of persistent ectopic pregnancy.

3. Blood progesterone test

Under normal circumstances, in the early stages of pregnancy, the progesterone level in pregnant women is mostly stable, and there are no abnormalities in the examination. However, when the progesterone test is performed at 8 weeks of pregnancy, if the progesterone value is less than 15ng per milliliter, which is significantly lower than the normal level, the possibility of ectopic pregnancy should be highly suspected. This test has a sensitivity of up to 95% for ectopic pregnancy and is an important method of diagnosis. The progesterone index has been listed as a routine monitoring item for ectopic pregnancy internationally.