Is there a relationship between endometrial thickening and functional uterine bleeding?

Endometrial thickening is a manifestation of functional uterine bleeding. In general, functional uterine bleeding in young women is mostly anovulatory, and changes in the proliferative phase are common. The main reason for endometrial thickening is that a large amount of estrogen stimulates the endometrium. Endometrial thickening is a manifestation of disease, and it is necessary to actively treat the disease behind endometrial thickening - functional uterine bleeding. If it is not actively treated, it will greatly affect conception. Because about 70% of functional uterine bleeding is accompanied by anovulation, without ovulation, there is no question of pregnancy.

Generally, the thickness of normal endometrium is 5-10mm. The thickness of endometrium changes with the menstrual cycle. During the ovarian cycle, when the follicles in the ovaries develop and mature, the endometrium proliferates under the action of estrogen secreted by the ovaries, which is called proliferative endometrium. After ovulation, the progesterone and estrogen secreted by the corpus luteum of the ovaries cause the proliferative endometrium to secrete, which is called secretory endometrium. After the corpus luteum in the ovaries degenerates, due to the decrease in the amount of estrogen and progesterone, the endometrium loses its support and becomes necrotic and flaky, which is manifested as menstruation. At this time, it is called menstrual endometrium. The thickness of endometrium is not constant.

If the endometrium does not change with such a cycle and shows signs of thickening, it indicates the presence of certain diseases, the most suspected of which is functional uterine bleeding. Ovarian hormone disorders and large amounts of estrogen stimulate the endometrium, which can easily lead to abnormal endometrial thickening. The clinical manifestations are irregular and excessive abnormal uterine bleeding. Patients may experience continuous bleeding after a long period of amenorrhea, which may be suspected of miscarriage clinically. It may also manifest as shortened cycles and prolonged menstruation, with bleeding time up to 1 month.