How to treat an invasive mole

How is an invasive mole treated?

1. Invasive mole is a gestational trophoblastic tumor that evolves from mole. That is, the molar vesicular tissue invades the myometrium and even penetrates the surface of the uterus and invades the parauterine tissue.

2. Invasive hydatidiform mole mostly occurs within 6 months after the hydatidiform mole is removed and is a malignant tumor. Common symptoms are irregular vaginal bleeding after the hydatidiform mole is expelled, blood HCG continues to not decrease or is negative or positive, and pregnancy is excluded. At this time, invasive hydatidiform mole should be considered. Once diagnosed, chemotherapy is the first choice, and surgery is a supplementary treatment.

3. If there is no desire to have children, total hysterectomy can be considered, with single-drug single-course adjuvant chemotherapy during the operation, and the decrease of blood HCG can be monitored after the operation to decide on further chemotherapy. For those who desire to have children, chemotherapy is the main method to monitor the changes of blood HCG and imaging examinations, understand the treatment effect of lesions at the metastatic site, and determine the course of chemotherapy.

4. Invasive hydatidiform mole mostly occurs within 6 months after the removal of hydatidiform mole and is a malignant tumor. After the treatment of hydatidiform mole, strict and effective contraception, regular follow-up, monitoring of blood HCG decline, and timely treatment of cough, hemoptysis, and irregular vaginal bleeding are required to diagnose invasive hydatidiform mole as soon as possible, treat it as soon as possible, choose the appropriate treatment plan, or improve the prognosis.