Why do uterine fibroids show low signal in T2 sequence? introduce: Uterine fibroids are a common gynecological disease, a benign tumor formed by the growth of smooth muscle cells in the uterine wall. In magnetic resonance imaging (MRI), uterine fibroids usually show low signals in the T2 sequence, which is of great clinical significance. This article will explore the reasons why uterine fibroids show low signals in the T2 sequence and explain their significance. 1. Basic principles of T2 sequence 2. Causes of T2 low signal 3. The significance of low T2 signal 1. Basic principles of T2 sequence MRI is a non-invasive medical imaging technique that uses magnetic resonance to observe the internal structure and function of the human body. MRI imaging is based on the intensity and characteristics of nuclear magnetic resonance signals, of which T1 and T2 sequences are among the most commonly used imaging sequences. The T2 sequence is very sensitive in showing fluid signals between tissues. 2. Causes of T2 low signal There may be many reasons why uterine fibroids show low signal in T2 sequence. Uterine fibroids are mainly composed of smooth muscle cells, and their cells and intercellular matrix may contain more fibrous tissue and collagen fibers. These tissue components show low signal in T2 sequence. Microbleeding, necrosis and fibrosis in uterine fibroids can also lead to reduced signal. Different uterine fibroid tissues have different intratumoral blood supply, and blood flow will also affect the intensity of T2 signal. 3. The significance of low T2 signal The low signal of uterine fibroids in the T2 sequence is of great clinical significance. This feature can help differentiate uterine fibroids from other gynecological diseases, such as endometriosis or adenomyosis. T2 low signal is often related to the growth pattern and biological behavior of uterine fibroids. Studies have shown that T2 low signal is associated with increased tumor volume, malignant degeneration and increased risk of recurrence. Therefore, by analyzing the T2 signal of uterine fibroids, it can provide an important reference for the selection of treatment options and the prognosis evaluation of the disease. The low signal of uterine fibroids in T2 sequence is mainly due to the characteristics of its tissue composition, such as increased content of fibrous tissue and collagen fibers, as well as the influence of microhemorrhage, necrosis and other factors. T2 low signal is of great significance in differential diagnosis and prognostic evaluation. Future studies should further explore the potential of using T2 low signal as a biological feature of uterine fibroids in MRI and enhance the understanding of its clinical significance to optimize the diagnosis and treatment of uterine fibroids. |
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