What causes endometrial thickening?

Endometrial thickening is a common gynecological disease that can cause many harms. Many patients do not understand its cause. Therefore, patients often ask such questions: what causes the endometrium to be too thick? Generally speaking, endometrium thickening is caused by the following reasons.

1. Distribution of hormone receptors

Complex endometrial thickening is related to the distribution of hormone receptors. This type of endometrial thickening may be polyp-like, and complex endometrial thickening may be mixed with other types of thickening such as uterine atrophy.

2. Ovarian dysfunction

If the ovarian hormones are disordered, it can easily lead to abnormal endometrial thickening, which is called endometrial hyperplasia. The clinical manifestations are irregular and excessive abnormal uterine bleeding. Patients may experience continuous bleeding after a long period of amenorrhea. Some patients also have shortened cycles and prolonged menstruation, and the bleeding time can be up to 1 month.

3. Abnormal estrogen secretion

The hormone secretion of hormones in female glands is unbalanced, resulting in anovulation. The endometrium is affected by estrogen for a long time, and there is no transformation of the cyclical secretion period. The endometrium is in a thickened state for a long time. This is a common factor in the thickening of the endometrium in women.

4. Endocrine Functional Tumors

Functional endocrine tumors lead to abnormal gonadotropin function of the pituitary gland and the occurrence of ovarian granulosa cell tumors, which can also cause thickening of the endometrium in women.

5. Obesity

The adrenal glands of obese women secrete androstenedione, which is converted into estrone after the action of aromatase in the adipose tissue. The estrone level in the plasma rises, which makes it easy for persistent estrogen effects to occur, causing thickening of the female endometrium.

The above is an introduction to the causes of endometrial thickening. It is recommended that patients seek timely treatment to avoid adverse effects on treatment due to severe illness. If you don’t know whether you have this disease, it is best to have a gynecological checkup once a year.