Primary amenorrhea is seen in patients with congenital reproductive tract abnormalities, congenital ovarian hypoplasia or absence, primary pituitary hypogonadism, and congenital adrenal hyperplasia. The following examinations should be performed: Gynecological examination During the examination, attention should be paid to the development of the vulva and the distribution of the vagina, whether there is clitoral hypertrophy, the development of the vagina, whether the vagina and hymen are obstructed, deformed, or atrophied, the richness and size of the ovaries, and whether the ovaries are enlarged. General examination Attention should be paid to general development and nutritional status, neuropsychiatric type, intelligence level, and physical deformity. If necessary, height, weight, finger length, and development of secondary sexual characteristics, as well as obesity, hirsutism, and galactorrhea, should be measured. Ovarian function test Vaginal mucus crystal examination: understand estrogen levels; cervical mucus crystal examination: understand estrogen levels and whether there is any influence of progesterone; basal body temperature measurement: understand whether ovulation and corpus luteum function occur; estrogen and progesterone level measurement: understand ovarian function. Uterine examination Laparoscopic examination: understand the depth, width, shape of the uterine cavity, whether there are any deformities, whether there are any adhesions, and take samples of the endometrium to check for any pathological changes; laparoscopic examination: directly observe the appearance of the uterus and gonads to exclude congenital developmental abnormalities, and take an ovarian biopsy when necessary; hystero-tubal iodized oil angiography: understand the shape of the uterine cavity, whether there are any deformities, whether the fallopian tubes are unobstructed, and exclude tuberculosis; drug test examination: progesterone and estrogen tests to observe whether the endometrium reacts. |
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