What are the diagnostic criteria for vulvar leukoplakia?

What are the diagnostic criteria for vulvar leukoplakia? The diagnostic criteria for vulvar leukoplakia are severe vulvar itching, whitening, thickening, roughness, softening of the vulvar skin, and thinning, dryness, and easy cracking. Biopsy and pathological examination can confirm the diagnosis. Let's ask the experts to give a detailed introduction.

What are the diagnostic criteria for vulvar leukoplakia? Experts believe that there are the following:

1. Itching of the vulva, sometimes with burning and pain. The skin of the affected area is rough, thickened like moss, with scratches, and sometimes chapped. Local pigmentation is reduced, and the labia majora and labia minora generally turn white. Mild atrophy can be seen on the vulva. In severe cases, the clitoris, labia majora and labia minora atrophy and adhesion, the labia minora partially or completely disappear, and then tighten, the vaginal opening is narrow, elasticity disappears, and even urination and sexual life are affected.

2. In addition to the above-mentioned specific symptoms and signs, the final conclusion should be based on pathological diagnosis. Because many diseases can cause skin itching and loss or depigmentation of pigments, although the manifestations are different, it is difficult to distinguish them with the naked eye. Even if the naked eye can diagnose, it is difficult to achieve pathological typing, especially to find atypical hyperplasia (precancerous lesions) early. It has been reported in the literature that about 50% of vulvar squamous cell carcinomas are often accompanied by vulvar white lesions.

3. In case of atypical lesions or chronic chapped skin, localized thickening, or ulceration, a biopsy must be performed to confirm the diagnosis. When sampling, samples should be collected from multiple points of the lesion: ulcers, chapped skin, nodules, protrusions, or rough areas, and the sampling should be appropriate. Method: 1% toluidine blue can be applied to the lesion area first, and then 1% acetic acid solution can be used to decolorize it after it dries. In the non-decolorized area, biopsy forceps can be used to perpendicularly hold the skin and reach deep into the dermis to obtain biopsy. Any non-decolorized area indicates that there are naked nuclei in the area, which suggests that biopsy in this area can improve the accuracy of diagnosis.

The above introduces the key points of vulvar leukoplakia diagnosis. Benign keratotic lesions in the vulva are called white keratosis. White keratosis that does not heal for a long time may further develop into vulvar leukoplakia. If you want to know more about the diagnosis of vulvar leukoplakia, please consult an online expert.

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