Gynecological diseases Precursors of uterine fibroids

Uterine fibroids are one of the most common benign tumors in the female reproductive organs and one of the most common tumors in the human body. They are also called fibroids and uterine fibroids. Because uterine fibroids are mainly composed of the proliferation of uterine smooth muscle cells and a small amount of fibrous connective tissue exists as supporting tissue, they are more accurately called uterine leiomyoma. They are also called uterine fibroids for short.

The etiology of uterine fibroids is still unclear and may involve a more complex interaction between normal myometrial cell mutations, sex hormones, and local growth factors.

According to a large number of observations and experimental results, uterine fibroids are a hormone-dependent tumor. Estrogen is the main factor that promotes the growth of fibroids. Scholars believe that growth hormone is related to the growth of fibroids. Growth hormone can cooperate with estrogen to promote mitosis and promote fibroid growth. It is speculated that placental lactogen can also cooperate with estrogen to promote mitosis. It is believed that the accelerated growth of uterine fibroids during pregnancy is not only related to the high hormone environment of pregnancy, but placental lactogen may also be involved. Ovarian function and hormone metabolism are controlled and regulated by higher nerve centers, so nerve center activity may also play an important role in the onset of fibroids. Because uterine fibroids are more common in women of childbearing age, widowed women, and women with uncoordinated sexual life. Long-term sexual dysfunction and chronic pelvic congestion may also be one of the causes of uterine fibroids.

Uterine fibroids have no precursors, and even if there are small fibroids on the uterine body, there will be no symptoms. But as the fibroids increase, some corresponding symptoms will appear. For example, if the uterine fibroids between the muscle walls continue to increase, it will cause menstrual changes, shortened menstrual cycles, or prolonged menstruation. Some people will experience dysmenorrhea, and some people will experience lower abdominal pain and increased vaginal discharge. Although submucosal uterine fibroids are relatively small, the symptoms appear earlier, mainly manifested as menstrual changes, such as increased menstrual volume and irregular vaginal bleeding. The main reason is that submucosal uterine fibroids protrude from the uterine cavity, which relatively increases the area of ​​the endometrium, affects uterine contraction, and causes menstrual changes.