What medicine is better for uterine fibroids? Treatment methods for uterine fibroids

Since uterine fibroids are related to estrogen, most drugs used to treat fibroids are related to lowering estrogen levels or antagonizing estrogen. Commonly used drugs include:

Introduction to commonly used drugs for uterine fibroids

1. Gonadotropin-releasing hormone agonist (GnRHa)

GnRHa can cause amenorrhea in most patients. Three months of treatment can reduce the volume of fibroids by about 35-65%, but within a few months after stopping the drug, the size of the fibroids will gradually return to the size before treatment. Therefore, its effect is temporary. It is mainly used for laparoscopic surgery or hysteroscopic surgery for large fibroids.

2. Aromatase inhibitors

Aromatase inhibitors reduce estrogen production in the ovarian and peripheral tissues, lowering estrogen levels. These drugs work faster based on their mechanism of action, but with far fewer side effects than GnRH-like drugs. Aromatase inhibitors can reduce the size and symptoms of uterine fibroids.

3. Mifepristone

Mifepristone's antiprogestin activity works on the higher-than-normal levels of progesterone receptors in uterine fibroids. Several studies have shown that high doses of mifepristone can reduce the size of fibroids by about 26-74%. Compared with the use of gonadotropin analogs, its effect is lower, and the recurrence rate of fibroids is lower after stopping mifepristone. With mifepristone, the amenorrhea rate can reach 90%, bone density remains stable, and pelvic compression is improved. Side effects of mifepristone include endometrial hyperplasia, endometrial cancer, and transient transaminases.

Treatments for uterine fibroids

1. Drug diagnosis and treatment:

For patients with severe conditions, drug diagnosis and treatment can only be a temporary treatment, not a permanent treatment, and cannot completely cure uterine fibroids. Since the drug contains hormones, long-term use will not improve the condition, so this method is still suitable for patients with milder conditions.

2. Surgical treatment:

The surgical treatment method is to completely remove the fibroids in the uterus, so that the patient can recover quickly and reduce the harm of the disease to her health. However, surgical treatment can usually be performed for patients who do not have fertility requirements.

3. Minimally invasive surgery:

It is usually laparoscopic treatment, which makes up for the deficiencies of traditional Chinese medicine and surgical treatment, and can enable patients to recover their health as soon as possible. The risk of surgical treatment is relatively reduced, because it is a minimally invasive surgery, the wound is very small, which can satisfy women's beauty psychology.