Hormone treatment is usually used to treat menopausal dysfunctional uterine bleeding

Menopausal functional uterine bleeding is mainly treated conservatively, and patients generally choose hormone therapy.

Progesterone

Progesterone can make the endometrium change to the secretory phase and then fall off to stop bleeding. For those with little bleeding, 10-20 mg of progesterone can be used daily, and bleeding can usually stop within 2-3 days. For those with long bleeding time and heavy blood loss, the treatment time should be extended, and a large amount of artificial synthetic progesterone can be taken orally, and the dosage should be gradually reduced after bleeding stops.

Androgens

Androgens can improve the hyperplasia of the endometrium, produce negative feedback and inhibit hypothalamic function, reduce the secretion of follicle-stimulating hormone and luteinizing hormone, and thus reduce the secretion of ovarian estrogen, and strengthen the tension of uterine muscles and uterine blood vessels; reduce pelvic congestion, reduce bleeding, and promote protein synthesis, thereby improving the patient's overall condition. Usage: When the menstrual blood volume is heavy, 25-50 mg of testosterone propionate can be injected intramuscularly daily for 3 consecutive days. The total amount of androgens per month should not exceed 300 mg to avoid adverse reactions such as hirsutism, acne, hoarseness, etc.

Continuous use of testosterone alone

Patients can choose to use testosterone alone continuously to suppress ovarian function. Usage: sublingual methyltestosterone 5mg, twice a day, or oral 10mg, once a day, for 20 consecutive days, stop for 10 days and continue the same treatment, which can be used for 3-6 months. This method is simpler and has no withdrawal bleeding, but it should be used with caution in patients with hypertension, cardiovascular disease and liver damage.