How to improve the cure rate of hyperprolactinemia

Many friends at work rarely have time to pay attention to women's health. How to treat hyperprolactinemia? Hyperprolactinemia is common in gynecological endocrine diseases. The body is affected by internal and external environmental factors (physiological or pathological), and the level of prolactin in the blood increases. When the increase reaches a certain standard, it is called hyperprolactinemia. So, how to improve the cure rate of hyperprolactinemia?

1. Treatment of the cause and primary disease

For example, eliminate adverse mental stimulation, stop taking HPRL-inducing drugs, and actively treat primary diseases such as pituitary tumors, hypothyroidism, Cushing's disease, etc.

2. Ovulation induction therapy

It is suitable for HPRL, anovulatory infertility, and those who cannot successfully ovulate and become pregnant after simple bromocriptine treatment. That is, a comprehensive therapy with bromocriptine as the main drug and other ovulation-inducing drugs: ① bromocriptine-CC-hCG; ② bromocriptine-hMG-hCG; ③ GnRH. Pulse therapy-bromocriptine, etc. Comprehensive therapy can save anti-prolactin, shorten the treatment cycle and increase the ovulation rate and pregnancy rate.

3. Surgical treatment

It is suitable for patients with giant adenomas that present compression symptoms, as well as patients with drug-resistant tumors, patients who are ineffective in bromocriptine treatment, and patients with multiple pituitary hormone secretion in sphenoid cell tumors. The current transsphenoidal microsurgery is safe, convenient, and easy to perform, and its efficacy is similar to that of bromocriptine therapy. The combination of bromocriptine before and after surgery can improve the efficacy. The disadvantages of the surgery are: for patients with pituitary tumors without obvious capsules and unclear boundaries, the surgery is not easy to be thorough or may cause damage, resulting in cerebrospinal fluid nasal fistula and secondary hypopituitarism.

4. Radiation therapy

It is suitable for non-functional tumors of the HP system and those who have not responded to drug and surgical treatment. Irradiation methods include: deep X-ray, 60Co, α particles and proton rays. Isotope 90 yttrium, 198 gold pituitary implantation, etc.

Through the above introduction, I believe that everyone has a certain understanding of the treatment measures for hyperprolactinemia. Here we need to emphasize that the disease is very harmful, so once you get this disease, you must receive treatment as soon as possible.